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[(1S,2R)-1-苄基-2-羟基-3-[异丁基[(4-硝基苯基)磺酰基]氨基]丙基]氨基甲酸叔丁酯

tert-Butyl [(1S,2R)-1-benzyl-2-hydroxy-3-[isobutyl[(4-nitrophenyl)sulfonyl]amino]propyl]carbamate

CAS: 191226-98-9

Molecular Formula: C25H35N3O7S

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  5. [(1S,2R)-1-苄基-2-羟基-3-[异丁基[(4-硝基苯基)磺酰基]氨基]丙基]氨基甲酸叔丁酯

[(1S,2R)-1-苄基-2-羟基-3-[异丁基[(4-硝基苯基)磺酰基]氨基]丙基]氨基甲酸叔丁酯 - Names and Identifiers

Name tert-Butyl [(1S,2R)-1-benzyl-2-hydroxy-3-[isobutyl[(4-nitrophenyl)sulfonyl]amino]propyl]carbamate
Synonyms tert-Butyl ((2S,3R)-3-hydroxy-4-(N-isobutyl-4-nitro-phenylsulfonamido)-1-phenylbutan-2-yl)carb
tert-Butyl[(1S,2R)-1-benzyl-2-hydroxy-3-[isobutyl[(4-nitrophenyl)sulfonyl]amino]propyl]carbamate
tert-Butyl (2S,3R)-3-hydroxy-4-(N-isobutyl-4-nitrophenylsulfonamido)-1-phenylbutan-2-ylcarbamate
tert-Butyl ((2S,3R)-3-hydroxy-4-(N-isobutyl-4-nitro-phenylsulfonamido)-1-phenylbutan-2-yl)carbama
tert-Butyl [(1S,2R)-1-benzyl-2-hydroxy-3-[isobutyl[(4-nitrophenyl)sulfonyl]amino]propyl]carbamate
tert-butyl [(2S,3R)-3-hydroxy-4-{(2-methylpropyl)[(4-nitrophenyl)sulfonyl]amino}-1-phenylbutan-2-yl]carbamate
[(1S,2R)-1-Benzyl-2-hydroxy-3-[isobutyl[(4-nitro-phenyl)sulfonyl)]amino]propyl]-carbamic Acid tert-Butyl Ester
N-[(1S,2R)-2-Hydroxy-3-[(2-methylpropyl)[(4-nitrophenyl)sulfonyl]amino]-1-(phenylmethyl)propyl]-carbamic Acid 1,1-Dimethylethyl Ester
CarbaMic acid,N-[(1S,2R)-2-hydroxy-3-[(2-Methylpropyl)[(4-nitrophenyl)sulfonyl]aMino]-1-(phenylMethyl)propyl]-,1,1-diMethylethyl ester
CAS 191226-98-9
InChI InChI=1/C25H35N3O7S/c1-18(2)16-27(36(33,34)21-13-11-20(12-14-21)28(31)32)17-23(29)22(15-19-9-7-6-8-10-19)26-24(30)35-25(3,4)5/h6-14,18,22-23,29H,15-17H2,1-5H3,(H,26,30)/t22-,23+/m0/s1

[(1S,2R)-1-苄基-2-羟基-3-[异丁基[(4-硝基苯基)磺酰基]氨基]丙基]氨基甲酸叔丁酯 - Physico-chemical Properties

Molecular FormulaC25H35N3O7S
Molar Mass521.63
Density1.241
Melting Point166-168 ºC
Solubility Acetone, Chloroform, Dichloromethane, Ethyl Acetate
AppearanceSolid
ColorWhite
pKa11.94±0.46(Predicted)
Storage ConditionRefrigerator
Refractive Index1.568

[(1S,2R)-1-苄基-2-羟基-3-[异丁基[(4-硝基苯基)磺酰基]氨基]丙基]氨基甲酸叔丁酯 - Introduction

(1S,2R)-1-benzyl-2-hydroxy-3-[isobutyl [(4-nitrophenyl)sulfonyl] amino] propyl] carbamic acid tert-butyl ester, also known as (1S,2R)-tert-Butyl N-[(4-nitrophenyl)sulfonyl]-(S)-3-(benzyloxy)-is an organic compound. The following is an introduction to its nature, use, preparation and safety information:

Nature:
-Appearance: White solid
-Molecular formula: C26H32N4O7S
-Molecular weight: 528.62g/mol
-Melting point: 128-130 ° C
-Solubility: Soluble in ethanol and chloroform, insoluble in water

Use:
The compound is commonly used in pharmaceutical synthesis and organic chemical reactions, as a catalyst, intermediate or reaction protecting group. It has symmetry and chiral structure, which is suitable for the synthesis of chiral drugs, especially in the synthesis of chiral acids.

Method:
(1S,2R)-1-benzyl-2-hydroxy-3-[isobutyl [(4-nitrophenyl)) the preparation method of sulfonyl] amino] propyl] carbamic acid tert-butyl ester is as follows:
1. React (1S,2R)-tert-Butyl N-[(4-nitrophenyl)sulfonyl]-(R)-with benzyl bromide in the presence of base.
2. The product is subjected to alkaline hydrolysis.
3. The final formic acid esterification reaction.

Safety Information:
No (1S,2R)-1-benzyl-2-hydroxy-3-[isobutyl [(4-nitrophenyl) detailed safety information report for tert-butyl sulfonyl] amino] propyl] carbamate. In view of the structural characteristics of this compound, Please strictly observe the laboratory safety practice when using it, and please refer to the relevant safety data sheet. Consult suppliers or experts at specialized chemical laboratories if required.
Last Update：2024-04-09 02:00:43
[(1S,2R)-1-苄基-2-羟基-3-[异丁基[(4-硝基苯基)磺酰基]氨基]丙基]氨基甲酸叔丁酯
Supplier List
Shanghai Yuanye Bio-Technology Co., Ltd.
Product Name: tert-Butyl [(1S,2R)-1-benzyl-2-hydroxy-3-[isobutyl[(4-nitrophenyl)sulfonyl]amino]propyl]carbamate Visit Supplier Webpage Request for quotation
CAS: 191226-98-9
Tel: 18301782025
Email: 3008007409@qq.com
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Shanghai Yuanye Bio-Technology Co., Ltd.
Product Name: tert-Butyl [(1S,2R)-1-benzyl-2-hydroxy-3-[isobutyl[(4-nitrophenyl)sulfonyl]amino]propyl]carbamate Visit Supplier Webpage Request for quotation
CAS: 191226-98-9
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409 Click to send a QQ message
View History
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